A TMD file contains title metadata used to verify the integrity and run Nintendo 3DS, Wii, and WiiU games. It stores metadata about the file that contains the actual game data, such as an APP, 3DS, or CIA file, and is referenced to decrypt and verify the contents of the game data file to launch the game. TMD files are typically distributed by Nintendo Update Servers (NUS).

TMD files may store varying metadata depending on the console the game is created to run on. For example, a TMD file for a WiiU game contains the required WiiUOS version, whereas a TMD file for a 3DS game will not include that information. Most 3DS, Wii, and WiiU gamers will not encounter a TMD file since it is referenced by the Nintendo console in the background when a game is launched. However, gamers who want to emulate a game on their computers will most likely see the TMD file (along with a TIK and CERT file) accompanying the main game data file.

3D model used by some games for the PlayStation console systems; saves the geometry (vertices and shapes) for the three-dimensional image; used for game characters, scenery, monsters, and other game objects.

An example PlayStation game that uses TMD files is Jurassic Park: Operation Genesis. Some TMD files can be viewed with MilkShape 3D, but without the coloring.

Document created by TextMaker, a word processing application that is part of SoftMaker Office; supports text, images, drawn objects, and page formatting properties; used to store authored documents.

TMD files were replaced by .TMDX files.